蟾毒靈
分析標準品,HPLC≥98%
Bufalin
CAS號：465-21-4
分子式： C24H34O4
分子量：386.53
MDL：MFCD00056525
貨號 | 規格/參數/品牌 | 價格 | 貨期 |
YJ-B20152-5mg | 分析標準品,HPLC≥98% | ￥600.00 | 現貨 |
YJ-B20152-20mg | 分析標準品,HPLC≥98% | ￥1020.00 | 現貨 |
YJ-B20152-100mg | 分析標準品,HPLC≥98% | ￥2980.00 | 現貨 |
產品介紹
熔點：242-243℃
沸點：556.6 ℃ at 760 mmHg
比旋光度：D -20°
外觀：針狀晶體
溶解性：DMSO : 100 mg/mL (258.72 mM; Need ultrasonic)
儲存條件：2-8℃
注意：部分產品我司僅能提供部分信息，我司不保證所提供信息的權威性，僅供客戶參考交流研究之用。
參考文獻(33篇)
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25. [IF=3.565] Liqiang Qian et al."Anti-tumor Activity of Bufalin by Inhibiting c-MET Mediated MEK/ERK and PI3K/AKT Signaling Pathways in Gallbladder Cancer."J Cancer. 2020; 11(11): 3114–3123
24. [IF=4.379] Cao Yueting et al."The impact of multiple climatic and geographic factors on the chemical defences of Asian toads (Bufo gargarizans Cantor)."Sci Rep-Uk. 2019 Nov;9(1):1-11
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20. [IF=2.311] Jinlin Xie et al."Bufalin suppresses the proliferation and metastasis of renal cell carcinoma by inhibiting the PI3K/Akt/mTOR signaling pathway."Oncol Lett. 2018 Sep;16(3):3867-3873
19. [IF=2.748] Tao Song et al."Bufalin, a bufanolide steroid from the parotoid glands of the Chinese toad, suppresses hERG K+ currents expressed in HEK293 cells."Fund Clin Pharmacol. 2017 Dec;31(6):695-700
18. [IF=2.748] Tao Song et al."Bufalin, a bufanolide steroid from the parotoid glands of the Chinese toad, inhibits L-type Ca2+ channels and contractility in rat ventricular myocytes."Fund Clin Pharmacol. 2017 Jun;31(3):340-346
17. [IF=3.743] Yu-Long Lan et al."Bufalin inhibits glioblastoma growth by promoting proteasomal degradation of the Na+/K+-ATPase α1 subunit."Biomed Pharmacother. 2018 Jul;103:204
16. [IF=4.101] Yao Liu et al."Effects of bufalin on the mTOR/p70S6K pathway and apoptosis in esophageal squamous cell carcinoma in nude mice."Int J Mol Med. 2017 Aug;40(2):357-366
15. [IF=6.284] Lan Yu-Long et al."The sodium pump α1 subunit regulates bufalin sensitivity of human glioblastoma cells through the p53 signaling pathway."Cell Biol Toxicol. 2019 Dec;35(6):521-539
14. Haiyan Hu, Qi Qi, Ziyi Dong, Xianglong Yu, Yujia Mo, Juyuan Luo, Yan Wang, Shouying Du, Yang Lu,
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12. Song, Tao, et al. "Bufalin, a bufanolide steroid from the parotoid glands of the Chinese toad, inhibits L‐type Ca2+ channels and contractility in rat ventricular myocytes." Fundamental & clinical pharmacology 31.3 (2017): 340-346.https:##doi.org/10.1111/fc
11. Song, Tao, et al. "Bufalin, a bufanolide steroid from the parotoid glands of the Chinese toad, suppresses hERG K+ currents expressed in HEK 293 cells." Fundamental & clinical pharmacology 31.6 (2017): 695-700.https:##doi.org/10.1111/fcp.12306
10. Liu, Yao, et al. "Effects of bufalin on the mTOR/p70S6K pathway and apoptosis in esophageal squamous cell carcinoma in nude mice." International journal of molecular medicine 40.2 (2017): 357-366. https:##doi.org/10.3892/ijmm.2017.3039
9. Liu, Yao, et al. "Effects of bufalin on the mTOR/p70S6K pathway and apoptosis in esophageal squamous cell carcinoma in nude mice." International journal of molecular medicine 40.2 (2017): 357-366. https:##doi.org/10.3892/ijmm.2017.3039
8. 曹月婷 崔可可 吳紀恒 等. 中華大蟾蜍毒液中蟾毒配基類成分的相關性研究[J]. 中國中藥雜志 2019(9).
7. 房蘊歌, 王鵬飛, 朱厚達,等. 蟾酥藥材和飲片(蟾酥粉)的質量標準研究[J]. 中國中藥雜志, 2020(8).
6. 張妹砣 李玉桑 葉曉雪. 六神丸血漿藥物化學的研究[J]. 綠色科技 2017 000(012):237-240.
5. 田志輝, 張培, 曹彥坤,等. 蟾蜍靈抑制食管癌細胞增殖、遷移和趨化運動的機制研究[J]. 中國現代醫學雜志, 2015(20):50-54.
4. 丁妍,王小玲,鄧會巖,蘇麗宏,張培,劉月平.蟾蜍靈抑制Raf/MEK/細胞外信號調節激酶信號通路活化影響人食管鱗癌細胞增殖及遷移機制研究[J].中國全科醫學,2015,18(21):2535-2541.
3. 陳硯凝, 劉堯, 王小玲,等. 蟾蜍令靈對裸鼠食管鱗癌原位移植瘤中 P70S6K 表達的影響[J]. 中國全科醫學, 2015(15期):1763-1767.
2. 張玲玲 韓金薇 王曉琳 et al. Bufalin抑制食管癌TE13細胞遷移機制探討[J]. 中華腫瘤防治雜志 2016 23(13):837-843.
1. 丁妍 王小玲 柳慧 等. Bufalin促進人食管癌細胞ECA109凋亡的研究[J]. 食管外科電子雜志 2014(02):49-54.
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