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甲基蓮心堿

分析標準品,HPLC≥98%

Neferine

CAS號：2292-16-2

分子式：C38H44N2O6

分子量：624.77

MDL：MFCD01707128

產品介紹

熔點：59-61℃

沸點：710.9℃ at 760 mmHg

比旋光度：-44.1°（c=0.301，氯仿）

外觀：無定形松散淡黃色粉末（乙mi）

溶解性：DMSO:  >15mg/mL

儲存條件：2-8℃

注意：部分產品我司僅能提供部分信息，我司不保證所提供信息的權威性，僅供客戶參考交流研究之用。

參考文獻(17篇)

17. [IF=4] Tan Lihua et al."In-vitro Evaluation of p-Sulfonatocalix[n] arenes (SCnA) as Novel Excipients Using a Vectorized BCS Approach."AAPS PHARMSCITECH.2025 Oct;26(7):1-17

16. [IF=8.2] Zhang Lilong et al."Neferine Ameliorates Severe Acute Pancreatitis-Associated Intestinal Injury by Promoting NRF2-mediated Ferroptosis."International Journal of Biological Sciences.2025 Apr;21(7):3247-3261

15. [IF=6.656] Ming?Yue Wang et al."Neferine ameliorates nonalcoholic steatohepatitis through regulating AMPK pathway."PHYTOMEDICINE.2023 Jun;114:154798

14. [IF=7.291] Yu Yuetong et al."Functional characterization and key residues engineering of a regio-promiscuity O-methyltransferases involved in benzylisoquinoline alkaloid biosynthesis in Nelumbo nucifera."Horticulture Research.2022 Dec;:

13. [IF=3.024] Xuan Yu et al."An innovative extraction strategy for herbal medicine by adopting p-sulphonatocalix[6]/[8]arenes."PHYTOCHEMICAL ANALYSIS

12. [IF=5.165] Juanning Ren et al."Qualitative and quantitative analysis of multi-components in Xing-Su-Ning Capsules for quality improvement."Arab J Chem. 2022 Jun;15:103825

11. [IF=1.842] Tu  Yixuan et al."Impact of harvesting time on the chemical composition and quality of fresh lotus seeds."Hortic Environ Biote. 2020 Aug;61(4):735-744

10. [IF=2.753]  Nabila    Jahan  et al."Neferine improves oxidative stress and apoptosis in benign prostate hyperplasia via Nrf2-ARE pathway.."Redox Rep. 2021;26(1):1-9

9. [IF=3] Qu  Lala et al."Phenotypic assessment and ligand screening of ETA/ETB receptors with label-free dynamic mass redistribution assay."N-S Arch Pharmacol. 2020 Jun;393(6):937-950

8. [IF=3.373] Na Zhang et al."TLC–MS identification of alkaloids in Leonuri Herba and Leonuri Fructus aided by a newly developed universal derivatisation reagent optimised by the response surface method."Phytochem Analysis. 2021 May;32(3):242-251

7. [IF=3.391] Yi Zhong et al."Neferine suppresses vascular endothelial inflammation by inhibiting the NF-κB signaling pathway."Arch Biochem Biophys. 2020 Dec;696:108595

6. [IF=4.225] Zhao  Ping et al."Neferine Promotes GLUT4 Expression and Fusion With the Plasma Membrane to Induce Glucose Uptake in L6 Cells."Front Pharmacol. 2019 Sep;0:999

5. [IF=5.279] Xianbao Deng et al."Analysis of Isoquinoline Alkaloid Composition and Wound-Induced Variation in Nelumbo Using HPLC-MS/MS."J Agr Food Chem. 2016;64(5):1130–1136

4.  Tu, Yixuan, Shoulei Yan, and Jie Li. "Impact of harvesting time on the chemical composition and quality of fresh lotus seeds." Horticulture, Environment, and Biotechnology 61.4 (2020): 735-744.

3.  隋月, 賀曉雙, 王嗣岑. 蓮子心中3種主要生物堿含量測定及提取優化[J]. 中國藥學雜志, 2018, 53(22):22-28.

2.  趙文芳, 李慧, 潘思軼,等. 膜組合方式對蓮子心水提物中活性成分分離的影響[J]. 中國食品學報, 2017, 17(008):165-169.

1.  魏萍,薛春苗,潘霖,雷珍珍,曹俊嶺.甲基蓮心堿對胰島素抵抗的HepG2細胞降糖的影響[J].臨床和實驗醫學雜志,2020,19(12):1283-1286.

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