荷葉堿
分析標準品,HPLC≥98%
Nuciferine
CAS號：475-83-2
分子式：C19H21NO2
分子量：295.376
MDL：MFCD01664592
貨號 | 規格/參數/品牌 | 價格 | 貨期 |
YJ-B20500-20mg | 分析標準品,HPLC≥98% | ￥600.00 | 現貨 |
YJ-B20500-200mg | 分析標準品,HPLC≥98% | ￥2500.00 | 現貨 |
JS27992-1g | 90% | ￥950.00 | 現貨 |
JS27992-5g | 90% | ￥2780.00 | 現貨 |
A10254-20mg | 分析標準品,含量91.3%，可溯源 | ￥1300.00 | 現貨 |
產品介紹
藥理藥效：具有減肥降脂的作用。
熔點：165.5℃
沸點：430.7℃at760mmHg
比旋光度：(c, 1 in EtOH)-164
外觀：白色粉末
溶解性：DMSO：3mg/ml
儲存條件：2-8℃
注意：部分產品我司僅能提供部分信息，我司不保證所提供信息的權威性，僅供客戶參考交流研究之用。
參考文獻(45篇)
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44. [IF=6.3] Shengnan Zhu et al."Nuciferine Exerts Anti-Inflammatory Effects in Mice With Non-Alcoholic Steatohepatitis by Regulating the miR-23a-3p-SIRT1-NF-κB Pathway and Akkermansia muciniphila-Extracellular Vesicles."PHYTOTHERAPY RESEARCH.2025 Jul;:
43. [IF=3.5] Zhiqiang Zhao et al."Nuciferine alleviates non-alcoholic steatohepatitis by restoring endoplasmic reticulum stress."EXPERIMENTAL CELL RESEARCH.2025 Jun;449:114599
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24. [IF=1.902] Yongjing Liu et al."Evaluation of Green and Efficient deep eutectic solvents as media for extracting Alkaloids from Lotus Leaf."Biomedical Chromatography. 2021 Dec 06
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22. [IF=3.373] Na Zhang et al."TLC–MS identification of alkaloids in Leonuri Herba and Leonuri Fructus aided by a newly developed universal derivatisation reagent optimised by the response surface method."Phytochem Analysis. 2021 May;32(3):242-251
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20. [IF=4.451] Haiyan Wen et al."Nuciferine attenuates the progression of osteoarthritis by targeting PI3K/Akt/NF-κB signaling pathway."J Funct Foods. 2021 Nov;86:104682
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18. [IF=3] Zhang Pengyu et al."Discovery of novel antagonists on β2-adrenoceptor from natural products using a label-free cell phenotypic assay."N-S Arch Pharmacol. 2018 Dec;391(12):1411-1420
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15. [IF=3.512] Thitirat Meelaph et al."Coregulation of Biosynthetic Genes and Transcription Factors for Aporphine-Type Alkaloid Production in Wounded Lotus Provides Insight into the Biosynthetic Pathway of Nuciferine."Acs Omega. 2018;3(8):8794–8802
14. [IF=5.279] Xianbao Deng et al."Analysis of Isoquinoline Alkaloid Composition and Wound-Induced Variation in Nelumbo Using HPLC-MS/MS."J Agr Food Chem. 2016;64(5):1130–1136
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12. Zhang, Lei, et al. "Direct coupling of thin-layer chromatography-bioautography with electrostatic field induced spray ionization-mass spectrometry for separation and identification of lipase inhibitors in lotus leaves." Analytica chimica acta 967 (2017): 5
11. Zhang, Lei, et al. "Direct coupling of thin-layer chromatography-bioautography with electrostatic field induced spray ionization-mass spectrometry for separation and identification of lipase inhibitors in lotus leaves." Analytica chimica acta 967 (2017): 5
10. Chen, X., Zheng, X., Zhang, M. et al. Nuciferine alleviates LPS-induced mastitis in mice via suppressing the TLR4-NF-κB signaling pathway. Inflamm. Res. 67, 903–911 (2018). https:##doi.org/10.1007/s00011-018-1183-2
9. Fugang Wang, Juan Cao, Xueqin Hou, Zhiyong Li & Xiaolan Qu (2018) Pharmacokinetics, tissue distribution, bioavailability, and excretion of nuciferine, an alkaloid from lotus, in rats by LC/MS/MS, Drug Development and Industrial Pharmacy, 44:9, 1557-1562, D
8. 鄭艷艷,李莉,袁曉慶,孔方,劉言娟.響應面法優化蝸牛酶輔助超聲提取荷葉總生物堿的工藝研究[J].安徽農業科學,2020,48(21):183-187.
7. 陳強,張華,沙玫,劉永靜.一測多評法同時測定荷葉中4種生物堿含量[J].福建中醫藥,2020,51(06):29-32.
6. 尹秀文, 侯成波, 陳江鵬,等. 采用在體單向腸灌流模型研究荷葉多成分整體的腸滲透性[J]. 中國中藥雜志, 2017, 42(008):1525-1531.
5. 李帆. 荷葉堿在青霉菌培養基中抑菌效果的研究[J]. 生物化工, 2018, 4(06):99-101.
4. 侯成波, 董月柳, 尹秀文,等. 荷葉多成分整體的腸滲透性研究[J]. 中國中藥雜志, 2016, 41(07):1183-1187.
3. 吳鵬,李慧芬,張學蘭,崔偉亮,王均秀.炒炭對荷葉主要化學成分轉化機制的研究[J].中成藥,2015,37(08):1767-1770.
2. 李夢杰 劉蘇珍 周斌 等. RP-HPLC法同時測定荷葉顆粒中3種有效成分的含量[J]. 中國藥房 2016(18期):2532-2534.
1. 夢杰 劉蘇珍 周斌 崔小弟 陳振華.HPLC法同時測定荷葉中的荷葉堿、蘆丁、槲皮素[J].中成藥 2016 38(01):111-114.
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